Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TRPM6	HGNC:17995 (HGNC) 140803 (Entrez Gene) 607009 (OMIM) TRPM6 (Alliance of Genome Resources)	Chr9 q21.13	Chr9:74722495-74888094 (-) GRCh38	intestinal hypomagnesemia 1 metal metabolism disorder	Q9BX84 (UniProt | EBI) NM_001177311 (RefSeq)
mouse	Trpm6	MGI:2675603 (MGI) 225997 (Entrez Gene) Gene Tree Trpm6 (Alliance of Genome Resources)	Chr19 13.21 cM	Chr19:18727347-18869875 (+) GRCm39		ENSMUSG00000024727 (Ensembl Gene Model) ENSMUSP00000037443 (Ensembl) ENSMUST00000040489 (Ensembl)
rat	Trpm6	RGD:1309942 (Rat Genome Database) 293874 (Entrez Gene) Trpm6 (Alliance of Genome Resources)	Chr1 q51			NP_001419090 (RefSeq) NM_001432161 (RefSeq)
zebrafish	trpm6	ZDB-GENE-111212-1 (Zebrafish Model Organism Database) 100149353 (Entrez Gene) trpm6 (Alliance of Genome Resources)	Chr5			NP_001238760 (RefSeq) NM_001251831 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.