Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TRPC4	HGNC:12336 (HGNC) 7223 (Entrez Gene) 603651 (OMIM) TRPC4 (Alliance of Genome Resources)	Chr13 q13.3	Chr13:37632063-37869802 (-) GRCh38	lung cancer	Q9UBN4 (UniProt | EBI) NM_001354806 (RefSeq)
mouse	Trpc4	MGI:109525 (MGI) 22066 (Entrez Gene) Gene Tree Trpc4 (Alliance of Genome Resources)	Chr3 25.43 cM	Chr3:54063456-54225892 (+) GRCm39		ENSMUSG00000027748 (Ensembl Gene Model) ENSMUSP00000029311 (Ensembl) ENSMUST00000029311 (Ensembl)
rat	Trpc4	RGD:621276 (Rat Genome Database) 84494 (Entrez Gene) Trpc4 (Alliance of Genome Resources)	Chr2 q26			O35119 (UniProt | EBI) NM_080396 (RefSeq)
zebrafish	trpc4a	ZDB-GENE-131217-1 (Zebrafish Model Organism Database) 102725537 (Entrez Gene) trpc4a (Alliance of Genome Resources)	Chr10			NP_001276811 (RefSeq) NM_001289882 (RefSeq)
	trpc4b	ZDB-GENE-120329-1 (Zebrafish Model Organism Database) 102725536 (Entrez Gene) trpc4b (Alliance of Genome Resources)	Chr15			NP_001276810 (RefSeq) NM_001289881 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.