Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TNFRSF11A	HGNC:11908 (HGNC) 8792 (Entrez Gene) 603499 (OMIM) TNFRSF11A (Alliance of Genome Resources)	Chr18 q21.33	Chr18:62325287-62391288 (+) GRCh38	autosomal recessive osteopetrosis 7 bone development disease familial expansile osteolysis osteoporosis Paget's disease of bone Paget's disease of bone 2	Q9Y6Q6 (UniProt | EBI) NM_001270949 (RefSeq)
mouse	Tnfrsf11a	MGI:1314891 (MGI) 21934 (Entrez Gene) Gene Tree Tnfrsf11a (Alliance of Genome Resources)	Chr1 49.7 cM	Chr1:105708443-105775709 (+) GRCm39	Paget's disease of bone	ENSMUSG00000026321 (Ensembl Gene Model) ENSMUSP00000027559 (Ensembl) ENSMUST00000027559 (Ensembl)
rat	Tnfrsf11a	RGD:1563614 (Rat Genome Database) 498206 (Entrez Gene) Tnfrsf11a (Alliance of Genome Resources)	Chr13 p11			NP_001258164 (RefSeq) NM_001271235 (RefSeq)
zebrafish	tnfrsf11a	ZDB-GENE-120910-2 (Zebrafish Model Organism Database) 100333821 (Entrez Gene) tnfrsf11a (Alliance of Genome Resources)	Chr24			XP_021329432 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.