Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NFKB1	HGNC:7794 (HGNC) 4790 (Entrez Gene) 164011 (OMIM) NFKB1 (Alliance of Genome Resources)	Chr4 q24	Chr4:102501330-102617302 (+) GRCh38	breast cancer common variable immunodeficiency 12 hepatocellular carcinoma lung non-small cell carcinoma melanoma prostate cancer tropical spastic paraparesis	P19838 (UniProt | EBI) NM_001382625 (RefSeq)
mouse	Nfkb1	MGI:97312 (MGI) 18033 (Entrez Gene) Gene Tree Nfkb1 (Alliance of Genome Resources)	Chr3 62.82 cM	Chr3:135290416-135397308 (-) GRCm39		ENSMUSG00000028163 (Ensembl Gene Model) ENSMUSP00000029812 (Ensembl) ENSMUST00000029812 (Ensembl)
rat	Nfkb1	RGD:70498 (Rat Genome Database) 81736 (Entrez Gene) Nfkb1 (Alliance of Genome Resources)	Chr2 q43			Q63369 (UniProt | EBI) NM_001276711 (RefSeq)
zebrafish	nfkb1	ZDB-GENE-121204-3 (Zebrafish Model Organism Database) 565756 (Entrez Gene) nfkb1 (Alliance of Genome Resources)	Chr14			XP_021336944 (RefSeq) NM_001353873 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.