Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL1R1	HGNC:5993 (HGNC) 3554 (Entrez Gene) 147810 (OMIM) IL1R1 (Alliance of Genome Resources)	Chr2 q11.2-q12.1	Chr2:102064544-102179874 (+) GRCh38	chronic recurrent multifocal osteomyelitis systemic scleroderma type 1 diabetes mellitus	P14778 (UniProt | EBI) NM_001320985 (RefSeq)
mouse	Il1r1	MGI:96545 (MGI) 16177 (Entrez Gene) Gene Tree Il1r1 (Alliance of Genome Resources)	Chr1 18.81 cM	Chr1:40264240-40356417 (+) GRCm39	type 1 diabetes mellitus	ENSMUSG00000026072 (Ensembl Gene Model) ENSMUSP00000027241 (Ensembl) ENSMUST00000027241 (Ensembl)
rat	Il1r1	RGD:2892 (Rat Genome Database) 25663 (Entrez Gene) Il1r1 (Alliance of Genome Resources)	Chr9 q22			Q02955 (UniProt | EBI) NM_001412593 (RefSeq)
zebrafish	zmp:0000000936	ZDB-GENE-130530-939 (Zebrafish Model Organism Database) 799204 (Entrez Gene) zmp:0000000936 (Alliance of Genome Resources)	Chr9			XP_021334731 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.