Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL1RN	HGNC:6000 (HGNC) 3557 (Entrez Gene) 147679 (OMIM) IL1RN (Alliance of Genome Resources)	Chr2 q14.1	Chr2:113099315-113134016 (+) GRCh38	acute kidney failure acute necrotizing pancreatitis allergic conjunctivitis alopecia areata anterior uveitis asthma autoimmune thrombocytopenic purpura bronchopulmonary dysplasia calcium oxalate nephrolithiasis chronic kidney disease chronic obstructive pulmonary disease chronic recurrent multifocal osteomyelitis common cold corneal neovascularization crescentic glomerulonephritis dacryocystitis depressive disorder diabetic angiopathy end stage renal disease glomerulonephritis graft-versus-host disease Graves ophthalmopathy hemolytic-uremic syndrome Henoch-Schoenlein purpura herpes simplex virus keratitis hypertension IgA glomerulonephritis inflammatory bowel disease keratoconus learning disability listeriosis lung non-small cell carcinoma melanoma middle cerebral artery infarction Muckle-Wells syndrome multiple myeloma nephrotic syndrome osteoporosis periodontitis pleural tuberculosis pleurisy pneumonia proteinuria pulmonary fibrosis pulmonary hypertension pulmonary tuberculosis renal cell carcinoma rheumatoid arthritis rhinitis Schnitzler syndrome sciatic neuropathy silicosis Sjogren's syndrome stomach cancer systemic lupus erythematosus toxic shock syndrome transient cerebral ischemia type 1 diabetes mellitus type 2 diabetes mellitus ulcerative colitis ureteral obstruction urinary bladder cancer vascular disease	P18510 (UniProt | EBI) NM_173843 (RefSeq)
mouse	Il1rn	MGI:96547 (MGI) 16181 (Entrez Gene) Gene Tree Il1rn (Alliance of Genome Resources)	Chr2 16.36 cM	Chr2:24226872-24241503 (+) GRCm39		16181 (NCBI Gene Model) P25085 (UniProt | EBI) NM_001039701 (RefSeq)
rat	Il1rn	RGD:621159 (Rat Genome Database) 60582 (Entrez Gene) Il1rn (Alliance of Genome Resources)	Chr3 p13			P25086 (UniProt | EBI) NM_022194 (RefSeq)
zebrafish	il1fma	ZDB-GENE-140106-231 (Zebrafish Model Organism Database) 102997062 (Entrez Gene) il1fma (Alliance of Genome Resources)	Chr11			NP_001277347 (RefSeq) NM_001290418 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.