JAK2 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	JAK2	HGNC:6192 (HGNC) 3717 (Entrez Gene) 147796 (OMIM) JAK2 (Alliance of Genome Resources)	Chr9 p24.1	Chr9:4984390-5129948 (+) GRCh38	acute myeloid leukemia ankylosing spondylitis Budd-Chiari syndrome colon adenocarcinoma Crohn's disease esophageal carcinoma essential thrombocythemia familial erythrocytosis 1 leukemia liver cancer lung adenocarcinoma lung non-small cell carcinoma myelofibrosis myeloid neoplasm polycythemia vera portal hypertension stomach cancer thrombocytosis thrombosis ulcerative colitis	O60674 (UniProt \| EBI) NM_001322196 (RefSeq)
mouse	Jak2	MGI:96629 (MGI) 16452 (Entrez Gene) Gene Tree Jak2 (Alliance of Genome Resources)	Chr19 23.73 cM	Chr19:29229228-29290480 (+) GRCm39	essential thrombocythemia myelofibrosis myeloproliferative neoplasm polycythemia vera	ENSMUSG00000024789 (Ensembl Gene Model) ENSMUSP00000064394 (Ensembl) ENSMUST00000065796 (Ensembl)
rat	Jak2	RGD:2939 (Rat Genome Database) 24514 (Entrez Gene) Jak2 (Alliance of Genome Resources)	Chr1 q52			Q62689 (UniProt \| EBI) NM_031514 (RefSeq)
zebrafish	jak2a	ZDB-GENE-980526-481 (Zebrafish Model Organism Database) 30307 (Entrez Gene) jak2a (Alliance of Genome Resources)	Chr21			NP_571168 (RefSeq) NM_131093 (RefSeq)
zebrafish	jak2b	ZDB-GENE-980526-123 (Zebrafish Model Organism Database) 30298 (Entrez Gene) jak2b (Alliance of Genome Resources)	Chr5			NP_571162 (RefSeq) NM_131087 (RefSeq)