Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LHX3	HGNC:6595 (HGNC) 8022 (Entrez Gene) 600577 (OMIM) LHX3 (Alliance of Genome Resources)	Chr9 q34.3	Chr9:136196250-136205128 (-) GRCh38	panhypopituitarism	Q9UBR4 (UniProt | EBI) NM_001363746 (RefSeq)
mouse	Lhx3	MGI:102673 (MGI) 16871 (Entrez Gene) Gene Tree Lhx3 (Alliance of Genome Resources)	Chr2 18.44 cM	Chr2:26090224-26098261 (-) GRCm39	hypopituitarism	16871 (NCBI Gene Model) P50481 (UniProt | EBI) NM_001039653 (RefSeq)
rat	Lhx3	RGD:71078 (Rat Genome Database) 170671 (Entrez Gene) Lhx3 (Alliance of Genome Resources)	Chr3 p13			NP_001413926 (RefSeq) NM_001426997 (RefSeq)
zebrafish	lhx3	ZDB-GENE-980526-131 (Zebrafish Model Organism Database) 30455 (Entrez Gene) lhx3 (Alliance of Genome Resources)	Chr5			Q90421 (UniProt | EBI) NM_131208 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.