Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EN2	HGNC:3343 (HGNC) 2020 (Entrez Gene) 131310 (OMIM) EN2 (Alliance of Genome Resources)	Chr7 q36.3	Chr7:155458129-155464831 (+) GRCh38	autistic disorder	P19622 (UniProt | EBI) NM_001427 (RefSeq)
mouse	En2	MGI:95390 (MGI) 13799 (Entrez Gene) Gene Tree En2 (Alliance of Genome Resources)	Chr5 13.94 cM	Chr5:28370692-28377164 (+) GRCm39	autism spectrum disorder	ENSMUSG00000039095 (Ensembl Gene Model) ENSMUSP00000036761 (Ensembl) ENSMUST00000036177 (Ensembl)
rat	En2	RGD:1561842 (Rat Genome Database) 499964 (Entrez Gene) En2 (Alliance of Genome Resources)	Chr4 q11			NP_001102684 (RefSeq) NM_001109214 (RefSeq)
zebrafish	en2a	ZDB-GENE-980526-167 (Zebrafish Model Organism Database) 30243 (Entrez Gene) en2a (Alliance of Genome Resources)	Chr7			P09015 (UniProt | EBI) NM_131044 (RefSeq)
	en2b	ZDB-GENE-980526-40 (Zebrafish Model Organism Database) 30238 (Entrez Gene) en2b (Alliance of Genome Resources)	Chr2			P31533 (UniProt | EBI) NM_131040 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.