Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CCND1	HGNC:1582 (HGNC) 595 (Entrez Gene) 168461 (OMIM) CCND1 (Alliance of Genome Resources)	Chr11 q13.3		acute myeloid leukemia colorectal cancer head and neck squamous cell carcinoma hepatocellular carcinoma high grade glioma invasive lobular carcinoma lung adenocarcinoma lung non-small cell carcinoma lung small cell carcinoma multiple myeloma non-Hodgkin lymphoma ovarian carcinoma pancreatic cancer pancreatic ductal adenocarcinoma renal cell carcinoma squamous cell carcinoma von Hippel-Lindau disease	P24385 (UniProt | EBI) NM_053056 (RefSeq)
mouse	Ccnd1	MGI:88313 (MGI) 12443 (Entrez Gene) Gene Tree Ccnd1 (Alliance of Genome Resources)	Chr7 88.92 cM	Chr7:144483668-144493568 (-) GRCm39		12443 (NCBI Gene Model) P25322 (UniProt | EBI) NM_001379248 (RefSeq)
rat	Ccnd1	RGD:68384 (Rat Genome Database) 58919 (Entrez Gene) Ccnd1 (Alliance of Genome Resources)	Chr1 q42			P39948 (UniProt | EBI) NM_171992 (RefSeq)
zebrafish	ccnd1	ZDB-GENE-980526-176 (Zebrafish Model Organism Database) 30222 (Entrez Gene) ccnd1 (Alliance of Genome Resources)	Chr7			Q90459 (UniProt | EBI) NM_131025 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.