Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTCH1	HGNC:9585 (HGNC) 5727 (Entrez Gene) 601309 (OMIM) PTCH1 (Alliance of Genome Resources)	Chr9 q22.32	Chr9:95442980-95517057 (-) GRCh38	basal cell carcinoma basaloid squamous cell carcinoma holoprosencephaly holoprosencephaly 7 lung adenocarcinoma lung squamous cell carcinoma nevoid basal cell carcinoma syndrome nevoid basal cell carcinoma syndrome 1 stomach cancer	Q13635 (UniProt | EBI) NM_000264 (RefSeq)
mouse	Ptch1	MGI:105373 (MGI) 19206 (Entrez Gene) Gene Tree Ptch1 (Alliance of Genome Resources)	Chr13 32.8 cM	Chr13:63656142-63721274 (-) GRCm39	basal cell carcinoma medulloblastoma nevoid basal cell carcinoma syndrome	19206 (NCBI Gene Model) Q61115 (UniProt | EBI) NM_008957 (RefSeq)
rat	Ptch1	RGD:621425 (Rat Genome Database) 89830 (Entrez Gene) Ptch1 (Alliance of Genome Resources)	Chr17 p14			NP_446018 (RefSeq) NM_053566 (RefSeq)
zebrafish	ptch1	ZDB-GENE-980526-196 (Zebrafish Model Organism Database) 30189 (Entrez Gene) ptch1 (Alliance of Genome Resources)	Chr8			NP_001292471 (RefSeq) NM_001305542 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.