Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TCF7L1	HGNC:11640 (HGNC) 83439 (Entrez Gene) 604652 (OMIM) TCF7L1 (Alliance of Genome Resources)	Chr2 p11.2			Q9HCS4 (UniProt | EBI) NM_031283 (RefSeq)
mouse	Tcf7l1	MGI:1202876 (MGI) 21415 (Entrez Gene) Gene Tree Tcf7l1 (Alliance of Genome Resources)	Chr6 32.27 cM	Chr6:72603354-72766028 (-) GRCm39		21415 (NCBI Gene Model) Q9Z1J1 (UniProt | EBI) NM_001079822 (RefSeq)
rat	Tcf7l1	RGD:1311671 (Rat Genome Database) 312451 (Entrez Gene) Tcf7l1 (Alliance of Genome Resources)	Chr4 q32			NP_001101335 (RefSeq) NM_001107865 (RefSeq)
zebrafish	tcf7l1a	ZDB-GENE-980605-30 (Zebrafish Model Organism Database) 30523 (Entrez Gene) tcf7l1a (Alliance of Genome Resources)	Chr10			Q9YHE8 (UniProt | EBI) NM_131269 (RefSeq)
	tcf7l1b	ZDB-GENE-991110-10 (Zebrafish Model Organism Database) 30556 (Entrez Gene) tcf7l1b (Alliance of Genome Resources)	Chr8			Q800Q5 (UniProt | EBI) NM_131296 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.