Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDX1	HGNC:6107 (HGNC) 3651 (Entrez Gene) 600733 (OMIM) PDX1 (Alliance of Genome Resources)	Chr13 q12.2	Chr13:27920000-27926313 (+) GRCh38	cerebral infarction hyperglycemia maturity-onset diabetes of the young type 4 pancreatic agenesis type 2 diabetes mellitus	P52945 (UniProt | EBI) NM_000209 (RefSeq)
mouse	Pdx1	MGI:102851 (MGI) 18609 (Entrez Gene) Gene Tree Pdx1 (Alliance of Genome Resources)	Chr5 86.84 cM	Chr5:147206907-147212658 (+) GRCm39	maturity-onset diabetes of the young maturity-onset diabetes of the young type 4 type 1 diabetes mellitus	18609 (NCBI Gene Model) P52946 (UniProt | EBI) NM_008814 (RefSeq)
rat	Pdx1	RGD:62387 (Rat Genome Database) 29535 (Entrez Gene) Pdx1 (Alliance of Genome Resources)	Chr12			P52947 (UniProt | EBI) NM_022852 (RefSeq)
zebrafish	pdx1	ZDB-GENE-990415-122 (Zebrafish Model Organism Database) 30721 (Entrez Gene) pdx1 (Alliance of Genome Resources)	Chr24			NP_571518 (RefSeq) NM_131443 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.