Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HTT	HGNC:4851 (HGNC) 3064 (Entrez Gene) 613004 (OMIM) HTT (Alliance of Genome Resources)	Chr4 p16.3	Chr4:3041363-3243960 (+) GRCh38	Huntington's disease Parkinson's disease	P42858 (UniProt | EBI) NM_001388492 (RefSeq)
mouse	Htt	MGI:96067 (MGI) 15194 (Entrez Gene) Gene Tree Htt (Alliance of Genome Resources)	Chr5 17.92 cM	Chr5:34919084-35069878 (+) GRCm39	Huntington's disease	15194 (NCBI Gene Model) P42859 (UniProt | EBI) NM_010414 (RefSeq)
rat	Htt	RGD:68337 (Rat Genome Database) 29424 (Entrez Gene) Htt (Alliance of Genome Resources)	Chr14 q21			P51111 (UniProt | EBI) NM_024357 (RefSeq)
zebrafish	htt	ZDB-GENE-990415-131 (Zebrafish Model Organism Database) 30214 (Entrez Gene) htt (Alliance of Genome Resources)	Chr1			NP_571093 (RefSeq) NM_131018 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.