Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PPARG	HGNC:9236 (HGNC) 5468 (Entrez Gene) 601487 (OMIM) PPARG (Alliance of Genome Resources)	Chr3 p25.2	Chr3:12287368-12434356 (+) GRCh38	Alzheimer's disease cardiovascular system disease carotid artery disease cognitive disorder colon cancer end stage renal disease familial partial lipodystrophy type 3 hypertension lipodystrophy obesity pancreatic cancer pre-eclampsia proliferative diabetic retinopathy type 2 diabetes mellitus	P37231 (UniProt | EBI) NM_001354667 (RefSeq)
mouse	Pparg	MGI:97747 (MGI) 19016 (Entrez Gene) Gene Tree Pparg (Alliance of Genome Resources)	Chr6 53.41 cM	Chr6:115337912-115467360 (+) GRCm39	abdominal obesity-metabolic syndrome congenital generalized lipodystrophy type 2 familial partial lipodystrophy primary pulmonary hypertension systemic lupus erythematosus	ENSMUSG00000000440 (Ensembl Gene Model) ENSMUSP00000000450 (Ensembl) ENSMUST00000000450 (Ensembl)
rat	Pparg	RGD:3371 (Rat Genome Database) 25664 (Entrez Gene) Pparg (Alliance of Genome Resources)	Chr4 q42			O88275 (UniProt | EBI) NM_013124 (RefSeq)
zebrafish	pparg	ZDB-GENE-990415-213 (Zebrafish Model Organism Database) 557037 (Entrez Gene) pparg (Alliance of Genome Resources)	Chr11			NP_571542 (RefSeq) NM_131467 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.