Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RRM2	HGNC:10452 (HGNC) 6241 (Entrez Gene) 180390 (OMIM) RRM2 (Alliance of Genome Resources)	Chr2 p25.1	Chr2:10120698-10211725 (+) GRCh38	pancreatic cancer	P31350 (UniProt | EBI) NM_001165931 (RefSeq)
mouse	Rrm2	MGI:98181 (MGI) 20135 (Entrez Gene) Gene Tree Rrm2 (Alliance of Genome Resources)	Chr12 8.5 cM	Chr12:24758253-24764145 (+) GRCm39		20135 (NCBI Gene Model) P11157 (UniProt | EBI) NM_009104 (RefSeq)
rat	Rrm2	RGD:1598310 (Rat Genome Database) 362720 (Entrez Gene) Rrm2 (Alliance of Genome Resources)	Chr6 q16			Q4KLN6 (UniProt | EBI) NM_001025740 (RefSeq)
	Rrm2l1	RGD:2323655 (Rat Genome Database) 100359539 (Entrez Gene) Rrm2l1 (Alliance of Genome Resources)	Chr19			XP_038954019 (RefSeq)
zebrafish	rrm2	ZDB-GENE-990415-25 (Zebrafish Model Organism Database) 30733 (Entrez Gene) rrm2 (Alliance of Genome Resources)	Chr19			P79733 (UniProt | EBI) NM_131450 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.