Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	THRB	HGNC:11799 (HGNC) 7068 (Entrez Gene) 190160 (OMIM) THRB (Alliance of Genome Resources)	Chr3 p24.2	Chr3:24117153-24495756 (-) GRCh38	breast carcinoma cervix uteri carcinoma in situ prostate cancer renal cell carcinoma selective pituitary thyroid hormone resistance thyroid hormone resistance syndrome	P10828 (UniProt | EBI) NM_001354714 (RefSeq)
mouse	Thrb	MGI:98743 (MGI) 21834 (Entrez Gene) Gene Tree Thrb (Alliance of Genome Resources)	Chr14 7.08 cM	Chr14:4431611-4809435 (-) GRCm39	attention deficit hyperactivity disorder follicular thyroid carcinoma thyroid hormone resistance syndrome	ENSMUSG00000021779 (Ensembl Gene Model) ENSMUSP00000022304 (Ensembl) ENSMUST00000022304 (Ensembl)
rat	Thrb	RGD:3858 (Rat Genome Database) 24831 (Entrez Gene) Thrb (Alliance of Genome Resources)	Chr15 p16			P18113 (UniProt | EBI) NM_001270854 (RefSeq)
zebrafish	thrb	ZDB-GENE-990415-268 (Zebrafish Model Organism Database) 30607 (Entrez Gene) thrb (Alliance of Genome Resources)	Chr19			Q9PVE4 (UniProt | EBI) NM_131340 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.