Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DLX5	HGNC:2918 (HGNC) 1749 (Entrez Gene) 600028 (OMIM) DLX5 (Alliance of Genome Resources)	Chr7 q21.3	Chr7:97020396-97024950 (-) GRCh38	split hand-foot malformation 1 split hand-foot malformation 1 with sensorineural hearing loss	P56178 (UniProt | EBI) NM_005221 (RefSeq)
mouse	Dlx5	MGI:101926 (MGI) 13395 (Entrez Gene) Gene Tree Dlx5 (Alliance of Genome Resources)	Chr6 2.83 cM	Chr6:6877801-6882068 (-) GRCm39	split hand-foot malformation 1	13395 (NCBI Gene Model) P70396 (UniProt | EBI) NM_010056 (RefSeq)
rat	Dlx5	RGD:2506 (Rat Genome Database) 25431 (Entrez Gene) Dlx5 (Alliance of Genome Resources)	Chr4 q21			P50575 (UniProt | EBI) NM_012943 (RefSeq)
zebrafish	dlx5a	ZDB-GENE-990415-49 (Zebrafish Model Organism Database) 30569 (Entrez Gene) dlx5a (Alliance of Genome Resources)	Chr19			P50576 (UniProt | EBI) NM_131306 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.