Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FGF8	HGNC:3686 (HGNC) 2253 (Entrez Gene) 600483 (OMIM) FGF8 (Alliance of Genome Resources)	Chr10 q24.32	Chr10:101770109-101780371 (-) GRCh38	hypogonadotropic hypogonadism 6 with or without anosmia prostate carcinoma in situ	P55075 (UniProt | EBI) NM_033164 (RefSeq)
mouse	Fgf8	MGI:99604 (MGI) 14179 (Entrez Gene) Gene Tree Fgf8 (Alliance of Genome Resources)	Chr19 38.75 cM	Chr19:45725237-45731354 (-) GRCm39	DiGeorge syndrome tetralogy of Fallot	ENSMUSG00000025219 (Ensembl Gene Model) ENSMUSP00000026241 (Ensembl) ENSMUST00000026241 (Ensembl)
rat	Fgf8	RGD:70891 (Rat Genome Database) 29349 (Entrez Gene) Fgf8 (Alliance of Genome Resources)	Chr1 q54			NP_579820 (RefSeq) NM_133286 (RefSeq)
zebrafish	fgf8a	ZDB-GENE-990415-72 (Zebrafish Model Organism Database) 30538 (Entrez Gene) fgf8a (Alliance of Genome Resources)	Chr13			O57341 (UniProt | EBI) NM_131281 (RefSeq)
	fgf8b	ZDB-GENE-010122-1 (Zebrafish Model Organism Database) 65089 (Entrez Gene) fgf8b (Alliance of Genome Resources)	Chr1			Q805B2 (UniProt | EBI) NM_182856 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.