Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NOG	HGNC:7866 (HGNC) 9241 (Entrez Gene) 602991 (OMIM) NOG (Alliance of Genome Resources)	Chr17 q22	Chr17:56593699-56595611 (+) GRCh38	brachydactyly type B2 cleft lip craniosynostosis Huntington's disease hyperopia multiple synostoses syndrome 1 proximal symphalangism proximal symphalangism 1 tarsal-carpal coalition syndrome	Q13253 (UniProt | EBI) NM_005450 (RefSeq)
mouse	Nog	MGI:104327 (MGI) 18121 (Entrez Gene) Gene Tree Nog (Alliance of Genome Resources)	Chr11 54.34 cM	Chr11:89191464-89193158 (-) GRCm39	esophageal atresia/tracheoesophageal fistula	ENSMUSG00000048616 (Ensembl Gene Model) ENSMUSP00000061427 (Ensembl) ENSMUST00000061728 (Ensembl)
rat	Nog	RGD:3183 (Rat Genome Database) 25495 (Entrez Gene) Nog (Alliance of Genome Resources)	Chr10 q26			Q62809 (UniProt | EBI) NM_012990 (RefSeq)
zebrafish	nog1	ZDB-GENE-991206-8 (Zebrafish Model Organism Database) 30174 (Entrez Gene) nog1 (Alliance of Genome Resources)	Chr3			Q9W741 (UniProt | EBI) NM_130983 (RefSeq)
	nog3	ZDB-GENE-990714-8 (Zebrafish Model Organism Database) 30173 (Entrez Gene) nog3 (Alliance of Genome Resources)	Chr12			Q9YHV3 (UniProt | EBI) NM_130982 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.