Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TLE2	HGNC:11838 (HGNC) 7089 (Entrez Gene) 601041 (OMIM) TLE2 (Alliance of Genome Resources)	Chr19 p13.3	Chr19:2997639-3047635 (-) GRCh38		Q04725 (UniProt | EBI) NM_003260 (RefSeq)
mouse	Tle2	MGI:104635 (MGI) 21886 (Entrez Gene) Gene Tree Tle2 (Alliance of Genome Resources)	Chr10 39.72 cM	Chr10:81410395-81426679 (+) GRCm39		ENSMUSG00000034771 (Ensembl Gene Model) ENSMUSP00000121125 (Ensembl) ENSMUST00000146358 (Ensembl)
rat	Tle2	RGD:1306665 (Rat Genome Database) 299636 (Entrez Gene) Tle2 (Alliance of Genome Resources)	Chr7 q11			NP_001034102 (RefSeq) NM_001039013 (RefSeq)
zebrafish	tle2a	ZDB-GENE-030131-2826 (Zebrafish Model Organism Database) 565013 (Entrez Gene) tle2a (Alliance of Genome Resources)	Chr22			NP_001124076 (RefSeq) NM_001130604 (RefSeq)
	tle2b	ZDB-GENE-050208-677 (Zebrafish Model Organism Database) 564019 (Entrez Gene) tle2b (Alliance of Genome Resources)	Chr22			XP_021329162 (RefSeq)
	tle2c	ZDB-GENE-060512-84 (Zebrafish Model Organism Database) 692261 (Entrez Gene) tle2c (Alliance of Genome Resources)	Chr2			NP_001038703 (RefSeq) NM_001045238 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.