Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC12A3	HGNC:10912 (HGNC) 6559 (Entrez Gene) 600968 (OMIM) SLC12A3 (Alliance of Genome Resources)	Chr16 q13	Chr16:56865207-56915850 (+) GRCh38	essential hypertension Gitelman syndrome	P55017 (UniProt | EBI) NM_001126108 (RefSeq)
mouse	Slc12a3	MGI:108114 (MGI) 20497 (Entrez Gene) Gene Tree Slc12a3 (Alliance of Genome Resources)	Chr8 46.46 cM	Chr8:95055829-95092842 (+) GRCm39	Gitelman syndrome	ENSMUSG00000031766 (Ensembl Gene Model) ENSMUSP00000034218 (Ensembl) ENSMUST00000034218 (Ensembl)
rat	Slc12a3	RGD:3686 (Rat Genome Database) 54300 (Entrez Gene) Slc12a3 (Alliance of Genome Resources)	Chr19 p13-p12			P55018 (UniProt | EBI) NM_019345 (RefSeq)
zebrafish	slc12a3	ZDB-GENE-030131-9505 (Zebrafish Model Organism Database) 565439 (Entrez Gene) slc12a3 (Alliance of Genome Resources)	Chr18			NP_001038545 (RefSeq) NM_001045080 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.