Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TBX21	HGNC:11599 (HGNC) 30009 (Entrez Gene) 604895 (OMIM) TBX21 (Alliance of Genome Resources)	Chr17 q21.32	Chr17:47733236-47746122 (+) GRCh38	asthma, nasal polyps, and aspirin intolerance primary immunodeficiency disease	Q9UL17 (UniProt | EBI) NM_013351 (RefSeq)
mouse	Tbx21	MGI:1888984 (MGI) 57765 (Entrez Gene) Gene Tree Tbx21 (Alliance of Genome Resources)	Chr11 60.95 cM	Chr11:96988897-97006157 (-) GRCm39	asthma	ENSMUSG00000001444 (Ensembl Gene Model) ENSMUSP00000001484 (Ensembl) ENSMUST00000001484 (Ensembl)
rat	Tbx21	RGD:1308264 (Rat Genome Database) 303496 (Entrez Gene) Tbx21 (Alliance of Genome Resources)	Chr10 q31			NP_001100513 (RefSeq) NM_001107043 (RefSeq)
zebrafish	tbx21	ZDB-GENE-080104-3 (Zebrafish Model Organism Database) 797797 (Entrez Gene) tbx21 (Alliance of Genome Resources)	Chr12			NP_001164070 (RefSeq) NM_001170599 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.