Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC7A5	HGNC:11063 (HGNC) 8140 (Entrez Gene) 600182 (OMIM) SLC7A5 (Alliance of Genome Resources)	Chr16 q24.2	Chr16:87830023-87869507 (-) GRCh38	cholangiocarcinoma colon cancer hepatocellular carcinoma lung squamous cell carcinoma	Q01650 (UniProt | EBI) NM_003486 (RefSeq)
mouse	Slc7a5	MGI:1298205 (MGI) 20539 (Entrez Gene) Gene Tree Slc7a5 (Alliance of Genome Resources)	Chr8 Syntenic	Chr8:122607885-122634425 (-) GRCm39	autism spectrum disorder	20539 (NCBI Gene Model) Q9Z127 (UniProt | EBI) NM_011404 (RefSeq)
rat	Slc7a5	RGD:620639 (Rat Genome Database) 50719 (Entrez Gene) Slc7a5 (Alliance of Genome Resources)	Chr19 q12			Q63016 (UniProt | EBI) NM_017353 (RefSeq)
zebrafish	slc7a5	ZDB-GENE-080818-4 (Zebrafish Model Organism Database) 797250 (Entrez Gene) slc7a5 (Alliance of Genome Resources)	Chr25			NP_001121830 (RefSeq) NM_001128358 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.