Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC11A1	HGNC:10907 (HGNC) 6556 (Entrez Gene) 600266 (OMIM) SLC11A1 (Alliance of Genome Resources)	Chr2 q35	Chr2:218382029-218396894 (+) GRCh38	Behcet's disease Buruli ulcer disease Crohn's disease cutaneous leishmaniasis inflammatory bowel disease juvenile rheumatoid arthritis leprosy lymphoproliferative syndrome multiple sclerosis pulmonary tuberculosis rheumatoid arthritis sarcoidosis systemic lupus erythematosus systemic scleroderma tuberculosis type 1 diabetes mellitus ulcerative colitis urinary bladder cancer visceral leishmaniasis	P49279 (UniProt | EBI) NM_001032220 (RefSeq)
mouse	Slc11a1	MGI:1345275 (MGI) 18173 (Entrez Gene) Gene Tree Slc11a1 (Alliance of Genome Resources)	Chr1 38.54 cM	Chr1:74414354-74425221 (+) GRCm39		ENSMUSG00000026177 (Ensembl Gene Model) ENSMUSP00000027368 (Ensembl) ENSMUST00000027368 (Ensembl)
rat	Slc11a1	RGD:1601463 (Rat Genome Database) 316519 (Entrez Gene) Slc11a1 (Alliance of Genome Resources)	Chr9 q33			P70553 (UniProt | EBI) NM_001031658 (RefSeq)
zebrafish	slc11a2	ZDB-GENE-021115-1 (Zebrafish Model Organism Database) 678623 (Entrez Gene) slc11a2 (Alliance of Genome Resources)	Chr11			NP_001035460 (RefSeq) NM_001040370 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.