Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LRP4	HGNC:6696 (HGNC) 4038 (Entrez Gene) 604270 (OMIM) LRP4 (Alliance of Genome Resources)	Chr11 p11.2	Chr11:46856717-46918642 (-) GRCh38	Cenani-Lenz syndactyly syndrome congenital myasthenic syndrome 17 sclerosteosis 2	O75096 (UniProt | EBI) NM_002334 (RefSeq)
mouse	Lrp4	MGI:2442252 (MGI) 228357 (Entrez Gene) Gene Tree Lrp4 (Alliance of Genome Resources)	Chr2 50.63 cM	Chr2:91287856-91344124 (+) GRCm39	sclerosteosis 2	ENSMUSG00000027253 (Ensembl Gene Model) ENSMUSP00000028689 (Ensembl) ENSMUST00000028689 (Ensembl)
rat	Lrp4	RGD:619731 (Rat Genome Database) 83469 (Entrez Gene) Lrp4 (Alliance of Genome Resources)	Chr3 q24			Q9QYP1 (UniProt | EBI) NM_031322 (RefSeq)
zebrafish	lrp4	ZDB-GENE-130129-1 (Zebrafish Model Organism Database) 110351181 (Entrez Gene) lrp4 (Alliance of Genome Resources)	Chr7			XP_017212642 (RefSeq) NM_001351714 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.