Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TCOF1	HGNC:11654 (HGNC) 6949 (Entrez Gene) 606847 (OMIM) TCOF1 (Alliance of Genome Resources)	Chr5 q32-q33.1	Chr5:150357629-150400308 (+) GRCh38	Treacher Collins syndrome Treacher Collins syndrome 1	Q13428 (UniProt | EBI) NM_001371623 (RefSeq)
mouse	Tcof1	MGI:892003 (MGI) 21453 (Entrez Gene) Gene Tree Tcof1 (Alliance of Genome Resources)	Chr18 34.41 cM	Chr18:60946827-60982043 (-) GRCm39	Treacher Collins syndrome	ENSMUSG00000024613 (Ensembl Gene Model) ENSMUSP00000135639 (Ensembl) ENSMUST00000175934 (Ensembl)
rat	Tcof1	RGD:1309850 (Rat Genome Database) 291571 (Entrez Gene) Tcof1 (Alliance of Genome Resources)	Chr18 q12.1			NP_001382056 (RefSeq) NM_001395127 (RefSeq)
zebrafish	tcof1	ZDB-GENE-141219-12 (Zebrafish Model Organism Database) 100329277 (Entrez Gene) tcof1 (Alliance of Genome Resources)	Chr14			XP_002664303 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.