Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TTF1	HGNC:12397 (HGNC) 7270 (Entrez Gene) 600777 (OMIM) TTF1 (Alliance of Genome Resources)	Chr9 q34.13	Chr9:132375548-132406851 (-) GRCh38		Q15361 (UniProt | EBI) NM_001205296 (RefSeq)
mouse	Ttf1	MGI:105044 (MGI) 22130 (Entrez Gene) Gene Tree Ttf1 (Alliance of Genome Resources)	Chr2 19.38 cM	Chr2:28950274-28977668 (+) GRCm39		ENSMUSG00000026803 (Ensembl Gene Model) ENSMUSP00000097809 (Ensembl) ENSMUST00000100237 (Ensembl)
rat	Ttf1	RGD:1565673 (Rat Genome Database) 499766 (Entrez Gene) Ttf1 (Alliance of Genome Resources)	Chr3 p12			NP_001414125 (RefSeq) NM_001427196 (RefSeq)
zebrafish	ttf1.1	ZDB-GENE-030131-6913 (Zebrafish Model Organism Database) 334973 (Entrez Gene) ttf1.1 (Alliance of Genome Resources)	Chr5			NP_001353682 (RefSeq) NM_001366754 (RefSeq)
	ttf1.2	ZDB-GENE-100921-87 (Zebrafish Model Organism Database) 100334190 (Entrez Gene) ttf1.2 (Alliance of Genome Resources)	Chr5			NP_001353684 (RefSeq) NM_001366755 (RefSeq)
	ttf1.6	ZDB-GENE-041008-214 (Zebrafish Model Organism Database) 449954 (Entrez Gene) ttf1.6 (Alliance of Genome Resources)	Chr5			XP_068077650 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.