Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRFAM7A	HGNC:15781 (HGNC) 89832 (Entrez Gene) 609756 (OMIM) CHRFAM7A (Alliance of Genome Resources)	Chr15 q13.2	Chr15:30360566-30393900 (-) GRCh38		Q494W8 (UniProt | EBI) NM_139320 (RefSeq)
	CHRNA7	HGNC:1960 (HGNC) 1139 (Entrez Gene) 118511 (OMIM) CHRNA7 (Alliance of Genome Resources)	Chr15 q13.3	Chr15:31923438-32173018 (+) GRCh38	chronic obstructive pulmonary disease esophagus squamous cell carcinoma lung cancer lung non-small cell carcinoma malignant pleural mesothelioma schizophrenia	P36544 (UniProt | EBI) NM_001190455 (RefSeq)
mouse	Chrna7	MGI:99779 (MGI) 11441 (Entrez Gene) Gene Tree Chrna7 (Alliance of Genome Resources)	Chr7 34.47 cM	Chr7:62748440-62862274 (-) GRCm39	schizophrenia	11441 (NCBI Gene Model) P49582 (UniProt | EBI) NM_007390 (RefSeq)
rat	Chrna7	RGD:2348 (Rat Genome Database) 25302 (Entrez Gene) Chrna7 (Alliance of Genome Resources)	Chr1 q22			Q05941 (UniProt | EBI) NM_012832 (RefSeq)
zebrafish	chrna7a	ZDB-GENE-040108-3 (Zebrafish Model Organism Database) 394199 (Entrez Gene) chrna7a (Alliance of Genome Resources)	Chr7			NP_957513 (RefSeq) NM_201219 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.