Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TREX1	HGNC:12269 (HGNC) 11277 (Entrez Gene) 606609 (OMIM) TREX1 (Alliance of Genome Resources)	Chr3 p21.31	Chr3:48465811-48467645 (+) GRCh38	Aicardi-Goutieres syndrome Chilblain lupus retinal vasculopathy with cerebral leukodystrophy systemic lupus erythematosus	Q9NSU2 (UniProt | EBI) NM_033627 (RefSeq)
mouse	Trex1	MGI:1328317 (MGI) 22040 (Entrez Gene) Gene Tree Trex1 (Alliance of Genome Resources)	Chr9 59.63 cM	Chr9:108887000-108888791 (-) GRCm39	Aicardi-Goutieres syndrome cutaneous lupus erythematosus	22040 (NCBI Gene Model) Q91XB0 (UniProt | EBI) NM_011637 (RefSeq)
rat	Trex1	RGD:1311998 (Rat Genome Database) 100049583 (Entrez Gene) Trex1 (Alliance of Genome Resources)	Chr8			NP_001020160 (RefSeq) NM_001024989 (RefSeq)
zebrafish	plex9.1	ZDB-GENE-131127-357 (Zebrafish Model Organism Database) 101886651 (Entrez Gene) plex9.1 (Alliance of Genome Resources)	Chr25			XP_005174272 (RefSeq)
	plex9.2	ZDB-GENE-110411-9 (Zebrafish Model Organism Database) 100005742 (Entrez Gene) plex9.2 (Alliance of Genome Resources)	Chr25			NP_001373584 (RefSeq) NM_001386655 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.