Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LZTR1	HGNC:6742 (HGNC) 8216 (Entrez Gene) 600574 (OMIM) LZTR1 (Alliance of Genome Resources)	Chr22 q11.21	Chr22:20982269-20999032 (+) GRCh38	glioblastoma hepatocellular carcinoma hypertrophic cardiomyopathy neurilemmoma Noonan syndrome Noonan syndrome 10 Noonan syndrome 2 schwannomatosis schwannomatosis 2	Q8N653 (UniProt | EBI) NM_006767 (RefSeq)
mouse	Lztr1	MGI:1914113 (MGI) 66863 (Entrez Gene) Gene Tree Lztr1 (Alliance of Genome Resources)	Chr16 10.85 cM	Chr16:17326552-17344197 (+) GRCm39	Noonan syndrome 10	ENSMUSG00000022761 (Ensembl Gene Model) ENSMUSP00000023444 (Ensembl) ENSMUST00000023444 (Ensembl)
rat	Lztr1	RGD:1309100 (Rat Genome Database) 360745 (Entrez Gene) Lztr1 (Alliance of Genome Resources)	Chr11 q23			NP_001101796 (RefSeq) NM_001108326 (RefSeq)
zebrafish	lztr1	ZDB-GENE-030131-9564 (Zebrafish Model Organism Database) 792832 (Entrez Gene) lztr1 (Alliance of Genome Resources)	Chr5			NP_001074074 (RefSeq) NM_001080605 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.