Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CDKL5	HGNC:11411 (HGNC) 6792 (Entrez Gene) 300203 (OMIM) CDKL5 (Alliance of Genome Resources)	ChrX p22.13	ChrX:18425583-18653629 (+) GRCh38	developmental and epileptic encephalopathy 2 intellectual disability Rett syndrome visual epilepsy	O76039 (UniProt | EBI) NM_003159 (RefSeq)
mouse	Cdkl5	MGI:1278336 (MGI) 382253 (Entrez Gene) Gene Tree Cdkl5 (Alliance of Genome Resources)	ChrX 73.95 cM	ChrX:159567241-159777673 (-) GRCm39	developmental and epileptic encephalopathy 2	382253 (NCBI Gene Model) Q3UTQ8 (UniProt | EBI) NM_001421523 (RefSeq)
rat	Cdkl5	RGD:2324133 (Rat Genome Database) 100362725 (Entrez Gene) Cdkl5 (Alliance of Genome Resources)	ChrX			NP_001408462 (RefSeq) NM_001421533 (RefSeq)
zebrafish	cdkl5	ZDB-GENE-081022-110 (Zebrafish Model Organism Database) 559341 (Entrez Gene) cdkl5 (Alliance of Genome Resources)	Chr11			NP_001124243 (RefSeq) NM_001130771 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.