Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

 

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GBA1	HGNC:4177 (HGNC) 2629 (Entrez Gene) 606463 (OMIM) GBA1 (Alliance of Genome Resources)	Chr1 q22	Chr1:155234452-155244699 (-) GRCh38	Gaucher's disease Gaucher's disease perinatal lethal Gaucher's disease type I Gaucher's disease type II Gaucher's disease type III Gaucher's disease type IIIC late onset Parkinson's disease Lewy body dementia Parkinsonism Parkinson's disease	P04062 (UniProt | EBI) NM_001005742 (RefSeq)
mouse	Gba1	MGI:95665 (MGI) 14466 (Entrez Gene) Gene Tree Gba1 (Alliance of Genome Resources)	Chr3 39.01 cM	Chr3:89110235-89116273 (+) GRCm39	Gaucher's disease Gaucher's disease type I Gaucher's disease type II	ENSMUSG00000028048 (Ensembl Gene Model) ENSMUSP00000130660 (Ensembl) ENSMUST00000167998 (Ensembl)
rat	Gba1	RGD:1589149 (Rat Genome Database) 684536 (Entrez Gene) Gba1 (Alliance of Genome Resources)	Chr2			NP_001121111 (RefSeq) NM_001127639 (RefSeq)
zebrafish	gba1	ZDB-GENE-100922-270 (Zebrafish Model Organism Database) 559072 (Entrez Gene) gba1 (Alliance of Genome Resources)	Chr16			XP_687471 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.