Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DEFB4A	HGNC:2767 (HGNC) 1673 (Entrez Gene) 602215 (OMIM) DEFB4A (Alliance of Genome Resources)	Chr8 p23.1			O15263 (UniProt | EBI) NM_004942 (RefSeq)
	DEFB4B	HGNC:30193 (HGNC) 100289462 (Entrez Gene) DEFB4B (Alliance of Genome Resources)	Chr8			NP_001192195 (RefSeq) NM_001205266 (RefSeq)
mouse	Defb3	MGI:1351612 (MGI) 27358 (Entrez Gene) Gene Tree Defb3 (Alliance of Genome Resources)	Chr8 10.35 cM	Chr8:19343376-19345307 (+) GRCm39		ENSMUSG00000039775 (Ensembl Gene Model) ENSMUSP00000033852 (Ensembl) ENSMUST00000033852 (Ensembl)
rat	Defb3	RGD:1589572 (Rat Genome Database) 641623 (Entrez Gene) Defb3 (Alliance of Genome Resources)	Chr16			Q32ZI4 (UniProt | EBI) NM_001037548 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.