Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	F12	HGNC:3530 (HGNC) 2161 (Entrez Gene) 610619 (OMIM) F12 (Alliance of Genome Resources)	Chr5 q35.3	Chr5:177402133-177416583 (-) GRCh38	angioedema factor XII deficiency hereditary angioedema hereditary angioedema type III middle cerebral artery infarction myocardial infarction transient cerebral ischemia	P00748 (UniProt | EBI) NM_000505 (RefSeq)
mouse	F12	MGI:1891012 (MGI) 58992 (Entrez Gene) Gene Tree F12 (Alliance of Genome Resources)	Chr13 30.06 cM	Chr13:55565771-55574606 (-) GRCm39	factor XII deficiency	ENSMUSG00000021492 (Ensembl Gene Model) ENSMUSP00000021948 (Ensembl) ENSMUST00000021948 (Ensembl)
rat	F12	RGD:1359175 (Rat Genome Database) 306761 (Entrez Gene) F12 (Alliance of Genome Resources)	Chr17 p14			D3ZTE0 (UniProt | EBI) NM_001014006 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.