Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FCGR2A	HGNC:3616 (HGNC) 2212 (Entrez Gene) 146790 (OMIM) FCGR2A (Alliance of Genome Resources)	Chr1 q23.3	Chr1:161505430-161524048 (+) GRCh38	arthus reaction atherosclerosis autoimmune thrombocytopenic purpura coronary artery disease Crohn's disease cystic fibrosis dengue disease dengue hemorrhagic fever diffuse large B-cell lymphoma diffuse scleroderma factor VIII deficiency haemophilus meningitis hemolytic anemia hemolytic disease of the fetus lupus nephritis lymphoid leukemia lymphopenia malaria multiple myeloma neutropenia non-Hodgkin lymphoma osteoarthritis Plasmodium falciparum malaria respiratory system disease rheumatoid arthritis systemic lupus erythematosus temporal arteritis thrombocytopenia thrombosis ulcerative colitis visual epilepsy	P12318 (UniProt | EBI) NM_001375296 (RefSeq)
	FCGR2B	HGNC:3618 (HGNC) 2213 (Entrez Gene) 604590 (OMIM) FCGR2B (Alliance of Genome Resources)	Chr1 q23.3	Chr1:161647243-161678654 (+) GRCh38	autoimmune thrombocytopenic purpura glomerulonephritis lymphoid leukemia malaria systemic lupus erythematosus	P31994 (UniProt | EBI) NM_001386005 (RefSeq)
	FCGR2C	HGNC:15626 (HGNC) 9103 (Entrez Gene) 612169 (OMIM) FCGR2C (Alliance of Genome Resources)	Chr1 q23.3	Chr1:161581339-161605662 (+) GRCh38		P31995 (UniProt | EBI) NM_201563 (RefSeq)
mouse	Fcgr2b	MGI:95499 (MGI) 14130 (Entrez Gene) Gene Tree Fcgr2b (Alliance of Genome Resources)	Chr1 78.02 cM	Chr1:170786186-170804116 (-) GRCm39	malaria systemic lupus erythematosus	ENSMUSG00000026656 (Ensembl Gene Model) ENSMUSP00000027966 (Ensembl) ENSMUST00000027966 (Ensembl)
rat	Fcgr2b	RGD:631331 (Rat Genome Database) 289211 (Entrez Gene) Fcgr2b (Alliance of Genome Resources)	Chr13 q24			Q63203 (UniProt | EBI) NM_175756 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.