Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KIR2DL1	HGNC:6329 (HGNC) 3802 (Entrez Gene) 604936 (OMIM) KIR2DL1 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:54769793-54784322 (+) GRCh38	acquired immunodeficiency syndrome	P43626 (UniProt | EBI) NM_014218 (RefSeq)
	KIR2DL2	HGNC:6330 (HGNC) 3803 (Entrez Gene) 604937 (OMIM) KIR2DL2 (Alliance of Genome Resources)	Chr19 q13.4		autoimmune hepatitis	P43627 (UniProt | EBI) NM_014219 (RefSeq)
	KIR2DL3	HGNC:6331 (HGNC) 3804 (Entrez Gene) 604938 (OMIM) KIR2DL3 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:54738513-54753052 (+) GRCh38		P43628 (UniProt | EBI) NM_015868 (RefSeq)
	KIR2DL4	HGNC:6332 (HGNC) 3805 (Entrez Gene) 604945 (OMIM) KIR2DL4 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:54803610-54814517 (+) GRCh38		Q99706 (UniProt | EBI) NM_002255 (RefSeq)
	KIR2DL5A	HGNC:16345 (HGNC) 57292 (Entrez Gene) 605305 (OMIM) KIR2DL5A (Alliance of Genome Resources)	Chr19 p13.3			Q8N109 (UniProt | EBI) NM_020535 (RefSeq)
	KIR2DL5B	HGNC:16346 (HGNC) 553128 (Entrez Gene) 615727 (OMIM) KIR2DL5B (Alliance of Genome Resources)	Chr19 p13.3			Q8NHK3 (UniProt | EBI) NM_001018081 (RefSeq)
	KIR2DP1	HGNC:16344 (HGNC) 554300 (Entrez Gene) KIR2DP1 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:54754756-54767881 (+) GRCh38
	KIR2DS1	HGNC:6333 (HGNC) 3806 (Entrez Gene) 604952 (OMIM) KIR2DS1 (Alliance of Genome Resources)	Chr19 q13.4			Q14954 (UniProt | EBI) NM_014512 (RefSeq)
	KIR2DS2	HGNC:6334 (HGNC) 100132285 (Entrez Gene) 604953 (OMIM) KIR2DS2 (Alliance of Genome Resources)	Chr19			P43631 (UniProt | EBI) NM_001291695 (RefSeq)
	KIR2DS3	HGNC:6335 (HGNC) 3808 (Entrez Gene) 604954 (OMIM) KIR2DS3 (Alliance of Genome Resources)	Chr19 q13.4			Q14952 (UniProt | EBI) NM_012313 (RefSeq)
	KIR2DS4	HGNC:6336 (HGNC) 3809 (Entrez Gene) 604955 (OMIM) KIR2DS4 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:54832676-54848575 (+) GRCh38		P43632 (UniProt | EBI) NM_001281971 (RefSeq)
	KIR2DS5	HGNC:6337 (HGNC) 3810 (Entrez Gene) 604956 (OMIM) KIR2DS5 (Alliance of Genome Resources)	Chr19 q13.4			Q14953 (UniProt | EBI) NM_014513 (RefSeq)
	KIR3DL1	HGNC:6338 (HGNC) 3811 (Entrez Gene) 604946 (OMIM) KIR3DL1 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:54816468-54830778 (+) GRCh38	hepatitis C human immunodeficiency virus infectious disease malaria tuberculosis	P43629 (UniProt | EBI) NM_001322168 (RefSeq)
	KIR3DL2	HGNC:6339 (HGNC) 3812 (Entrez Gene) 604947 (OMIM) KIR3DL2 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:54850443-54867207 (+) GRCh38		P43630 (UniProt | EBI) NM_001242867 (RefSeq)
	KIR3DL3	HGNC:16312 (HGNC) 115653 (Entrez Gene) 610095 (OMIM) KIR3DL3 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:54724442-54736632 (+) GRCh38		Q8N743 (UniProt | EBI) NM_153443 (RefSeq)
	KIR3DP1	HGNC:16343 (HGNC) 548594 (Entrez Gene) KIR3DP1 (Alliance of Genome Resources)	Chr	Chr19:54786355-54790418 (+) GRCh38		NM_001015070 (RefSeq)
	KIR3DS1	HGNC:6340 (HGNC) 3813 (Entrez Gene) 620778 (OMIM) KIR3DS1 (Alliance of Genome Resources)	Chr19 q13.4		acquired immunodeficiency syndrome chronic fatigue syndrome COVID-19 dengue hemorrhagic fever hepatitis B hepatitis C hepatocellular carcinoma human cytomegalovirus infection human immunodeficiency virus infectious disease liver cirrhosis lymphoproliferative syndrome malaria Polyomavirus-associated nephropathy pulmonary tuberculosis syphilis tuberculosis West Nile fever	Q14943 (UniProt | EBI) NM_001083539 (RefSeq)
mouse	Kir3dl2	MGI:3612791 (MGI) 245615 (Entrez Gene) Gene Tree Kir3dl2 (Alliance of Genome Resources)	ChrX 58.45 cM	ChrX:135348856-135444805 (-) GRCm39		ENSMUSG00000057439 (Ensembl Gene Model) ENSMUSP00000071994 (Ensembl) ENSMUST00000072125 (Ensembl)
rat	Kir3dl1	RGD:727836 (Rat Genome Database) 353253 (Entrez Gene) Kir3dl1 (Alliance of Genome Resources)	Chr1 q12			P83556 (UniProt | EBI) NM_181479 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.