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Vertebrate Homology
Source
 Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)		 Associated Human Diseases Sequences
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human KLK1 HGNC:6357 (HGNC)
3816 (Entrez Gene)
147910 (OMIM)
KLK1 (Alliance of Genome Resources)
 Chr19 q13.33 Chr19:50819146-50823787 (-)
GRCh38 		cardiomyopathy
chronic kidney disease
end stage renal disease
hypertension
myocardial infarction
 P06870 (UniProt | EBI)
NM_002257 (RefSeq)
KLK2 HGNC:6363 (HGNC)
3817 (Entrez Gene)
147960 (OMIM)
KLK2 (Alliance of Genome Resources)
 Chr19 q13.33 Chr19:50861568-50880567 (+)
GRCh38 		P20151 (UniProt | EBI)
NM_001002231 (RefSeq)
KLK3 HGNC:6364 (HGNC)
354 (Entrez Gene)
176820 (OMIM)
KLK3 (Alliance of Genome Resources)
 Chr19 q13.33 Chr19:50854915-50860764 (+)
GRCh38 		P07288 (UniProt | EBI)
NM_001648 (RefSeq)
mouse Klk1b16 MGI:891982 (MGI)
16615 (Entrez Gene)
Gene Tree
Klk1b16 (Alliance of Genome Resources)
 Chr7 28.64 cM Chr7:43786191-43791034 (+)
GRCm39 		ENSMUSG00000038968 (Ensembl Gene Model)
ENSMUSP00000005933 (Ensembl)
ENSMUST00000005933 (Ensembl)
rat Klk1 RGD:2969 (Rat Genome Database)
24523 (Entrez Gene)
Klk1 (Alliance of Genome Resources)
 Chr1 q22 P36373 (UniProt | EBI)
NM_012593 (RefSeq)
Klk1c2 RGD:3888 (Rat Genome Database)
24841 (Entrez Gene)
Klk1c2 (Alliance of Genome Resources)
 Chr1 q22 P00759 (UniProt | EBI)
NM_012677 (RefSeq)
Klk1c3 RGD:735032 (Rat Genome Database)
292872 (Entrez Gene)
Klk1c3 (Alliance of Genome Resources)
 Chr1 q22 P15950 (UniProt | EBI)
NM_001271315 (RefSeq)
Klk1c6 RGD:1303220 (Rat Genome Database)
408242 (Entrez Gene)
Klk1c6 (Alliance of Genome Resources)
 Chr1 q22 NP_001382054 (RefSeq)
NM_001003977 (RefSeq)
Klk1c8 RGD:1305359 (Rat Genome Database)
292866 (Entrez Gene)
Klk1c8 (Alliance of Genome Resources)
 Chr1 q22 P36374 (UniProt | EBI)
NM_001013067 (RefSeq)
Klk1c9 RGD:727805 (Rat Genome Database)
292868 (Entrez Gene)
Klk1c9 (Alliance of Genome Resources)
 Chr1 q22 P07647 (UniProt | EBI)
NM_175759 (RefSeq)
Klk1c10 RGD:1561403 (Rat Genome Database)
292858 (Entrez Gene)
Klk1c10 (Alliance of Genome Resources)
 Chr1 q22 P36375 (UniProt | EBI)
NM_001135173 (RefSeq)
Klk1c12 RGD:1303192 (Rat Genome Database)
292855 (Entrez Gene)
Klk1c12 (Alliance of Genome Resources)
 Chr1 q22 P36376 (UniProt | EBI)
NM_001005382 (RefSeq)
Klk7 RGD:1306420 (Rat Genome Database)
292852 (Entrez Gene)
Klk7 (Alliance of Genome Resources)
 Chr1 q22 NP_001099724 (RefSeq)
NM_001106254 (RefSeq)
Klk10 RGD:1303242 (Rat Genome Database)
292850 (Entrez Gene)
Klk10 (Alliance of Genome Resources)
 Chr1 q22 NP_001004100 (RefSeq)
NM_001004100 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory