Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MMP1	HGNC:7155 (HGNC) 4312 (Entrez Gene) 120353 (OMIM) MMP1 (Alliance of Genome Resources)	Chr11 q22.2	Chr11:102789401-102798160 (-) GRCh38	abdominal aortic aneurysm aortic valve stenosis arteriosclerosis atherosclerosis atrial fibrillation Barrett's esophagus breast cancer carotid artery disease carotid stenosis cervical cancer congestive heart failure coronary artery disease dilated cardiomyopathy end stage renal disease epidermolysis bullosa dystrophica esophagus adenocarcinoma hypertension hypertrophic cardiomyopathy intermediate coronary syndrome localized scleroderma lung cancer myocardial infarction obstructive lung disease ocular hypertension ovarian cancer primary open angle glaucoma pulmonary emphysema renal cell carcinoma renal fibrosis skin melanoma thoracic aortic aneurysm thrombosis urinary bladder cancer varicose veins	P03956 (UniProt | EBI) NM_002421 (RefSeq)
mouse	Mmp1a	MGI:1933846 (MGI) 83995 (Entrez Gene) Gene Tree Mmp1a (Alliance of Genome Resources)	Chr9 2.46 cM	Chr9:7464141-7476857 (+) GRCm39		ENSMUSG00000043089 (Ensembl Gene Model) ENSMUSP00000151193 (Ensembl) ENSMUST00000217651 (Ensembl)
rat	Mmp1	RGD:1307917 (Rat Genome Database) 300339 (Entrez Gene) Mmp1 (Alliance of Genome Resources)	Chr8 q11			P81563 (UniProt | EBI) NM_001134530 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.