Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLCB1	HGNC:15917 (HGNC) 23236 (Entrez Gene) 607120 (OMIM) PLCB1 (Alliance of Genome Resources)	Chr20 p12.3	Chr20:8077251-8968360 (+) GRCh38	developmental and epileptic encephalopathy 12 myelodysplastic syndrome	Q9NQ66 (UniProt | EBI) NM_182734 (RefSeq)
mouse	Plcb1	MGI:97613 (MGI) 18795 (Entrez Gene) Gene Tree Plcb1 (Alliance of Genome Resources)	Chr2 65.66 cM	Chr2:134628084-135317178 (+) GRCm39	Alzheimer's disease schizophrenia	18795 (NCBI Gene Model) Q9Z1B3 (UniProt | EBI) NM_019677 (RefSeq)
rat	Plcb1	RGD:3344 (Rat Genome Database) 24654 (Entrez Gene) Plcb1 (Alliance of Genome Resources)	Chr3 q36			P10687 (UniProt | EBI) NM_001077641 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.