Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SIGLEC7	HGNC:10876 (HGNC) 27036 (Entrez Gene) 604410 (OMIM) SIGLEC7 (Alliance of Genome Resources)	Chr19 q13.41	Chr19:51142299-51153526 (+) GRCh38		Q9Y286 (UniProt | EBI) NM_014385 (RefSeq)
	SIGLEC8	HGNC:10877 (HGNC) 27181 (Entrez Gene) 605639 (OMIM) SIGLEC8 (Alliance of Genome Resources)	Chr19 q13.41	Chr19:51450847-51458456 (-) GRCh38		Q9NYZ4 (UniProt | EBI) NM_014442 (RefSeq)
	SIGLEC9	HGNC:10878 (HGNC) 27180 (Entrez Gene) 605640 (OMIM) SIGLEC9 (Alliance of Genome Resources)	Chr19 q13.41	Chr19:51119778-51136651 (+) GRCh38		Q9Y336 (UniProt | EBI) NM_001198558 (RefSeq)
	SIGLEC12	HGNC:15482 (HGNC) 89858 (Entrez Gene) 606094 (OMIM) SIGLEC12 (Alliance of Genome Resources)	Chr19 q13.41	Chr19:51491227-51501800 (-) GRCh38		Q96PQ1 (UniProt | EBI) NM_001412258 (RefSeq)
mouse	Siglece	MGI:1932475 (MGI) 83382 (Entrez Gene) Gene Tree Siglece (Alliance of Genome Resources)	Chr7 28.25 cM	Chr7:43300494-43309585 (-) GRCm39		83382 (NCBI Gene Model) Q91Y57 (UniProt | EBI) NM_031181 (RefSeq)
rat	Siglec8	RGD:1563073 (Rat Genome Database) 292846 (Entrez Gene) Siglec8 (Alliance of Genome Resources)	Chr1 q22			NP_001419063 (RefSeq) NM_001432134 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.