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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KRT6A HGNC:6443 (HGNC)
3853 (Entrez Gene)
148041 (OMIM)
KRT6A (Alliance of Genome Resources)
Chr12 q13.13 Chr12:52487176-52493257 (-)
GRCh38
pachyonychia congenita
P02538 (UniProt | EBI)
NM_005554 (RefSeq)
KRT6B HGNC:6444 (HGNC)
3854 (Entrez Gene)
148042 (OMIM)
KRT6B (Alliance of Genome Resources)
Chr12 q13.13 Chr12:52446651-52452146 (-)
GRCh38
pachyonychia congenita
P04259 (UniProt | EBI)
NM_005555 (RefSeq)
KRT6C HGNC:20406 (HGNC)
286887 (Entrez Gene)
612315 (OMIM)
KRT6C (Alliance of Genome Resources)
Chr12 q13.13 Chr12:52468516-52473805 (-)
GRCh38
focal or diffuse nonepidermolytic palmoplantar keratoderma
P48668 (UniProt | EBI)
NM_173086 (RefSeq)
mouse Krt6a MGI:1100845 (MGI)
16687 (Entrez Gene)
Gene Tree
Krt6a (Alliance of Genome Resources)
Chr15 56.97 cM Chr15:101598363-101602746 (-)
GRCm39
16687 (NCBI Gene Model)
P50446 (UniProt | EBI)
NM_008476 (RefSeq)
rat Krt6c RGD:1588056 (Rat Genome Database)
683313 (Entrez Gene)
Krt6c (Alliance of Genome Resources)
Chr7 Q4FZU2 (UniProt | EBI)
NM_001101007 (RefSeq)
zebrafish krt4 ZDB-GENE-000607-83 (Zebrafish Model Organism Database)
794486 (Entrez Gene)
krt4 (Alliance of Genome Resources)
Chr6 NP_571584 (RefSeq)
NM_131509 (RefSeq)
krt5 ZDB-GENE-991110-23 (Zebrafish Model Organism Database)
797351 (Entrez Gene)
krt5 (Alliance of Genome Resources)
Chr23 NP_571231 (RefSeq)
NM_131156 (RefSeq)
zgc:158846 ZDB-GENE-070209-50 (Zebrafish Model Organism Database)
100009654 (Entrez Gene)
zgc:158846 (Alliance of Genome Resources)
Chr6 NP_001076492 (RefSeq)
NM_001083023 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory