Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FGFR3	HGNC:3690 (HGNC) 2261 (Entrez Gene) 134934 (OMIM) FGFR3 (Alliance of Genome Resources)	Chr4 p16.3	Chr4:1793293-1808872 (+) GRCh38	acanthosis nigricans achondroplasia camptodactyly-tall stature-scoliosis-hearing loss syndrome cervix carcinoma colorectal cancer craniosynostosis Crouzon syndrome-acanthosis nigricans syndrome epidermal nevus Human papillomavirus infectious disease hypochondroplasia lacrimoauriculodentodigital syndrome 2 Muenke Syndrome oral squamous cell carcinoma SADDAN thanatophoric dysplasia transitional cell carcinoma urinary bladder cancer	P22607 (UniProt | EBI) NM_001163213 (RefSeq)
mouse	Fgfr3	MGI:95524 (MGI) 14184 (Entrez Gene) Gene Tree Fgfr3 (Alliance of Genome Resources)	Chr5 17.83 cM	Chr5:33879068-33894412 (+) GRCm39	achondroplasia autosomal dominant disease hypochondroplasia Muenke Syndrome scoliosis thanatophoric dysplasia	14184 (NCBI Gene Model) Q61851 (UniProt | EBI) NM_001359036 (RefSeq)
rat	Fgfr3	RGD:620714 (Rat Genome Database) 84489 (Entrez Gene) Fgfr3 (Alliance of Genome Resources)	Chr14 q21			NP_445881 (RefSeq) NM_053429 (RefSeq)
zebrafish	fgfr3	ZDB-GENE-000816-1 (Zebrafish Model Organism Database) 58129 (Entrez Gene) fgfr3 (Alliance of Genome Resources)	Chr13			Q9I8X3 (UniProt | EBI) NM_131606 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.