Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NKX2-1	HGNC:11825 (HGNC) 7080 (Entrez Gene) 600635 (OMIM) NKX2-1 (Alliance of Genome Resources)	Chr14 q13.3	Chr14:36516392-36521149 (-) GRCh38	choreatic disease papillary thyroid carcinoma	P43699 (UniProt | EBI) NM_003317 (RefSeq)
mouse	Nkx2-1	MGI:108067 (MGI) 21869 (Entrez Gene) Gene Tree Nkx2-1 (Alliance of Genome Resources)	Chr12 24.42 cM	Chr12:56578741-56583570 (-) GRCm39		21869 (NCBI Gene Model) P50220 (UniProt | EBI) NM_009385 (RefSeq)
rat	Nkx2-1	RGD:3866 (Rat Genome Database) 25628 (Entrez Gene) Nkx2-1 (Alliance of Genome Resources)	Chr6			P23441 (UniProt | EBI) NM_013093 (RefSeq)
zebrafish	nkx2.1	ZDB-GENE-010404-1 (Zebrafish Model Organism Database) 81883 (Entrez Gene) nkx2.1 (Alliance of Genome Resources)	Chr17			NP_571851 (RefSeq) NM_131776 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.