Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	VANGL2	HGNC:15511 (HGNC) 57216 (Entrez Gene) 600533 (OMIM) VANGL2 (Alliance of Genome Resources)	Chr1 q23.2	Chr1:160400564-160428670 (+) GRCh38	neural tube defect	Q9ULK5 (UniProt | EBI) NM_020335 (RefSeq)
mouse	Vangl2	MGI:2135272 (MGI) 93840 (Entrez Gene) Gene Tree Vangl2 (Alliance of Genome Resources)	Chr1 79.54 cM	Chr1:171828527-171856011 (-) GRCm39	neural tube defect	ENSMUSG00000026556 (Ensembl Gene Model) ENSMUSP00000159531 (Ensembl) ENSMUST00000247845 (Ensembl)
rat	Vangl2	RGD:1309442 (Rat Genome Database) 289229 (Entrez Gene) Vangl2 (Alliance of Genome Resources)	Chr13 q24			P84889 (UniProt | EBI) NM_001105969 (RefSeq)
zebrafish	vangl2	ZDB-GENE-020507-3 (Zebrafish Model Organism Database) 245949 (Entrez Gene) vangl2 (Alliance of Genome Resources)	Chr7			Q8UVJ6 (UniProt | EBI) NM_153674 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.