Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MSH6	HGNC:7329 (HGNC) 2956 (Entrez Gene) 600678 (OMIM) MSH6 (Alliance of Genome Resources)	Chr2 p16.3	Chr2:47695530-47810101 (+) GRCh38	colorectal carcinoma endometrial cancer hereditary nonpolyposis colorectal cancer type 5 Lynch syndrome mismatch repair cancer syndrome	P52701 (UniProt | EBI) NM_001406832 (RefSeq)
mouse	Msh6	MGI:1343961 (MGI) 17688 (Entrez Gene) Gene Tree Msh6 (Alliance of Genome Resources)	Chr17 57.87 cM	Chr17:88282490-88298320 (+) GRCm39		ENSMUSG00000005370 (Ensembl Gene Model) ENSMUSP00000005503 (Ensembl) ENSMUST00000005503 (Ensembl)
rat	Msh6	RGD:2322311 (Rat Genome Database) 100360342 (Entrez Gene) Msh6 (Alliance of Genome Resources)	Chr6			NP_001385477 (RefSeq) NM_001398548 (RefSeq)
zebrafish	msh6	ZDB-GENE-020905-3 (Zebrafish Model Organism Database) 260437 (Entrez Gene) msh6 (Alliance of Genome Resources)	Chr13			NP_878280 (RefSeq) NM_182860 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.