Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADRA2A	HGNC:281 (HGNC) 150 (Entrez Gene) 104210 (OMIM) ADRA2A (Alliance of Genome Resources)	Chr10 q25.2	Chr10:111077029-111080907 (+) GRCh38	alcohol dependence attention deficit hyperactivity disorder familial partial lipodystrophy nicotine dependence substance abuse type 2 diabetes mellitus	P08913 (UniProt | EBI) NM_000681 (RefSeq)
mouse	Adra2a	MGI:87934 (MGI) 11551 (Entrez Gene) Gene Tree Adra2a (Alliance of Genome Resources)	Chr19 49.04 cM	Chr19:54033690-54037413 (+) GRCm39		11551 (NCBI Gene Model) Q01338 (UniProt | EBI) NM_007417 (RefSeq)
rat	Adra2a	RGD:2056 (Rat Genome Database) 25083 (Entrez Gene) Adra2a (Alliance of Genome Resources)	Chr1			P22909 (UniProt | EBI) NM_012739 (RefSeq)
zebrafish	adra2a	ZDB-GENE-021010-1 (Zebrafish Model Organism Database) 266750 (Entrez Gene) adra2a (Alliance of Genome Resources)	Chr22			Q90WY4 (UniProt | EBI) NM_207637 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.