Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CTSL	HGNC:2537 (HGNC) 1514 (Entrez Gene) 116880 (OMIM) CTSL (Alliance of Genome Resources)	Chr9 q21.33	Chr9:87724051-87731469 (+) GRCh38	hypertrophic cardiomyopathy	P07711 (UniProt | EBI) NM_001257972 (RefSeq)
	CTSV	HGNC:2538 (HGNC) 1515 (Entrez Gene) 603308 (OMIM) CTSV (Alliance of Genome Resources)	Chr9 q22.33	Chr9:97029677-97156556 (-) GRCh38		O60911 (UniProt | EBI) NM_001333 (RefSeq)
mouse	Ctsl	MGI:88564 (MGI) 13039 (Entrez Gene) Gene Tree Ctsl (Alliance of Genome Resources)	Chr13 33.26 cM	Chr13:64509704-64518586 (-) GRCm39	dilated cardiomyopathy	13039 (NCBI Gene Model) P06797 (UniProt | EBI) NM_001428552 (RefSeq)
rat	Ctsl	RGD:2448 (Rat Genome Database) 25697 (Entrez Gene) Ctsl (Alliance of Genome Resources)	Chr17 p14			P07154 (UniProt | EBI) NM_013156 (RefSeq)
zebrafish	ctsla	ZDB-GENE-030131-106 (Zebrafish Model Organism Database) 321453 (Entrez Gene) ctsla (Alliance of Genome Resources)	Chr5			NP_997749 (RefSeq) NM_212584 (RefSeq)
	ctslb	ZDB-GENE-980526-285 (Zebrafish Model Organism Database) 30443 (Entrez Gene) ctslb (Alliance of Genome Resources)	Chr12			NP_571273 (RefSeq) NM_131198 (RefSeq)
	ctsll	ZDB-GENE-041010-76 (Zebrafish Model Organism Database) 449826 (Entrez Gene) ctsll (Alliance of Genome Resources)	Chr5			NP_001005999 (RefSeq) NM_001005999 (RefSeq)
	si:dkey-239j18.2	ZDB-GENE-121214-52 (Zebrafish Model Organism Database) 321853 (Entrez Gene) si:dkey-239j18.2 (Alliance of Genome Resources)	Chr12			NP_001274132 (RefSeq) NM_001287203 (RefSeq)
	si:dkey-239j18.3	ZDB-GENE-121214-39 (Zebrafish Model Organism Database) 100001785 (Entrez Gene) si:dkey-239j18.3 (Alliance of Genome Resources)	Chr12			XP_001341714 (RefSeq)
	si:dkey-269i1.4	ZDB-GENE-121214-37 (Zebrafish Model Organism Database) 564835 (Entrez Gene) si:dkey-269i1.4 (Alliance of Genome Resources)	Chr12			NP_001099150 (RefSeq) NM_001105680 (RefSeq)
	zgc:174153	ZDB-GENE-080215-7 (Zebrafish Model Organism Database) 567623 (Entrez Gene) zgc:174153 (Alliance of Genome Resources)	Chr12			NP_001104662 (RefSeq) NM_001111192 (RefSeq)
	zgc:174154	ZDB-GENE-071004-116 (Zebrafish Model Organism Database) 100537591 (Entrez Gene) zgc:174154 (Alliance of Genome Resources)	Chr12			NP_001314908 (RefSeq) NM_001327979 (RefSeq)
	zgc:174855	ZDB-GENE-071004-74 (Zebrafish Model Organism Database) 569326 (Entrez Gene) zgc:174855 (Alliance of Genome Resources)	Chr12			NP_001096592 (RefSeq) NM_001103122 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.