Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SIN3A	HGNC:19353 (HGNC) 25942 (Entrez Gene) 607776 (OMIM) SIN3A (Alliance of Genome Resources)	Chr15 q24.2	Chr15:75369379-75455842 (-) GRCh38	chromosome 15q24 deletion syndrome	Q96ST3 (UniProt | EBI) NM_001145357 (RefSeq)
mouse	Sin3a	MGI:107157 (MGI) 20466 (Entrez Gene) Gene Tree Sin3a (Alliance of Genome Resources)	Chr9 30.89 cM	Chr9:56979324-57035650 (+) GRCm39		ENSMUSG00000042557 (Ensembl Gene Model) ENSMUSP00000130221 (Ensembl) ENSMUST00000168177 (Ensembl)
rat	Sin3a	RGD:1311598 (Rat Genome Database) 363067 (Entrez Gene) Sin3a (Alliance of Genome Resources)	Chr8 q24			NP_001382569 (RefSeq) NM_001108761 (RefSeq)
zebrafish	sin3aa	ZDB-GENE-070620-3 (Zebrafish Model Organism Database) 563090 (Entrez Gene) sin3aa (Alliance of Genome Resources)	Chr25			NP_001091650 (RefSeq) NM_001098180 (RefSeq)
	sin3ab	ZDB-GENE-030131-2066 (Zebrafish Model Organism Database) 323346 (Entrez Gene) sin3ab (Alliance of Genome Resources)	Chr7			XP_002662923 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.