Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP3A7	HGNC:2640 (HGNC) 1551 (Entrez Gene) 605340 (OMIM) CYP3A7 (Alliance of Genome Resources)	Chr7 q22.1	Chr7:99705036-99735196 (-) GRCh38		P24462 (UniProt | EBI) NM_000765 (RefSeq)
	CYP3A7-CYP3A51P	HGNC:51504 (HGNC) 100861540 (Entrez Gene) CYP3A7-CYP3A51P (Alliance of Genome Resources)	Chr7 q22.1	Chr7:99684677-99735196 (-) GRCh38		NP_001243426 (RefSeq) NM_001256497 (RefSeq)
	CYP3A43	HGNC:17450 (HGNC) 64816 (Entrez Gene) 606534 (OMIM) CYP3A43 (Alliance of Genome Resources)	Chr7 q22.1	Chr7:99828013-99866093 (+) GRCh38		Q9HB55 (UniProt | EBI) NM_057096 (RefSeq)
mouse	Cyp3a25	MGI:1930638 (MGI) 56388 (Entrez Gene) Gene Tree Cyp3a25 (Alliance of Genome Resources)	Chr5 85.17 cM	Chr5:145914004-145946428 (-) GRCm39		ENSMUSG00000029630 (Ensembl Gene Model) ENSMUSP00000065585 (Ensembl) ENSMUST00000068317 (Ensembl)
rat	Cyp3a18	RGD:628709 (Rat Genome Database) 252931 (Entrez Gene) Cyp3a18 (Alliance of Genome Resources)	Chr12 p11			Q64581 (UniProt | EBI) NM_145782 (RefSeq)
zebrafish	cyp3a65	ZDB-GENE-050604-1 (Zebrafish Model Organism Database) 553969 (Entrez Gene) cyp3a65 (Alliance of Genome Resources)	Chr1			NP_001032515 (RefSeq) NM_001037438 (RefSeq)
	cyp3c1	ZDB-GENE-030131-3060 (Zebrafish Model Organism Database) 324340 (Entrez Gene) cyp3c1 (Alliance of Genome Resources)	Chr3			NP_997838 (RefSeq) NM_212673 (RefSeq)
	cyp3c3	ZDB-GENE-041114-102 (Zebrafish Model Organism Database) 492759 (Entrez Gene) cyp3c3 (Alliance of Genome Resources)	Chr3			NP_001007401 (RefSeq) NM_001007400 (RefSeq)
	cyp3c4	ZDB-GENE-060929-96 (Zebrafish Model Organism Database) 558541 (Entrez Gene) cyp3c4 (Alliance of Genome Resources)	Chr3			NP_001071016 (RefSeq) NM_001077548 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.